Moves like the marine animals, the membrane which saves the heart News

To RESUME the movement of marine animals. The idea of the start-up of the French Corwave is simple: to revolutionize the market of pumps the heart thanks to a special membrane in the silicon which wants to help patients suffering from cardiovascular diseases to live better. The difference compared to the others is its undulating movement "similar to that of a fish-fin", according to the definition given by the ceo of the company Louis de Lillers , which reduces the possible complications. If the milestones will be met, soon to be made, the first trials on patients. The goal is to achieve the CE mark of the European Union and launch in the market of the pumps to the heart, that already in 2018, was worth more than a billion dollars.

According to data from the World Heart Federation, every year there are nearly 18 million deaths from cardiovascular disease. In Italy, the higher Institute of Health has noted that, in 2018, the heart problems are still the main cause of death, responsible for 44% of all deaths. And people who suffer from it then it becomes a chronically ill. To resolve these cases, often the only solution is heart transplantation, which, however, he runs the risk of rejection by the recipient. The development of the ventricular assist devices (VAD) represents a big step forward in the field of cardiology and the transplant in February 2019 in Kazakhstan of the first prototype wireless is proof of that. However, even in this field there is no lack of possible complications in the long term, such as bleeding, gastrointestinal distress, hemolysis, thrombus, and aortic insufficiency.

The cause of these problems is the engine a rotary current devices, which ensures a continuous flow of blood. For De Lillers "several studies have emphasized how the high-speed rotation of the blades, in the actual pumps of the cardiac present on the market and spoil the blood, altering the normal functioning of the human body". Damage that instead the device of the Corwave seems to not cause. The oscillation of the membrane silicone at regular intervals "allows you to faithfully reproduce the physiological flow of blood, adapting it to the needs of the patient and the pulsatility of the heart native," concludes De Lillers. The first tests proved to be encouraging. According to the biomedical engineer Giuseppe Cardone , which takes care of testing for the account of the company, "the device already shows promising results in order to restore the physiological flow of blood, minimizing or eliminating adverse effects".

The membrane is present on both “Nemo,” ventricular assist device for milder cases of heart failure, both on the “Neptune”, designed for the most severe cases. Thanks to the program Calipso, in collaboration with the hospital Group Pitié-Salpêtrière in Paris and with the University Centre of Lille, the start-up has received 14 million euro of funding over 4 years from public Bank investment French with the objective to optimize and to obtain the clinical validation of “Neptune”.

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