The 31st-seeded Pavlyuchenkova entered the afternoon with an 0-6 record in preceding singles quarterfinals at all major tournaments.
That included a loss at that point in 2011 at Roland Garros.
But the 29-year-old Pavlyuchenkova came out on top at Court Philippe Chatrier at a game that lasted more than 2 1/2 hours and ended to a double-fault from Rybakina.
The 21st-seeded Rybakina eliminated 23-time Grand Slam singles champion Serena Williams in straight sets in the fourth round.
Pavlyuchenkova will play in the final four to Thursday against the other woman making her Grand Slam semifinal introduction: Tamara Zidansek.
Pavlyuchenkova and Rybakina have been scheduled to be on precisely the exact same side of the court as a group in the doubles quarterfinals on Wednesday.
Defending French Open singles champion Iga Swiatek is trying to win the doubles title, also, and her and her partner are to the semifinals.
Swiatek will confront Maria Sakkari in the singles quarterfinals on Wednesday.
The last girl to win the singles and doubles titles at precisely the exact same year in the French Open was Mary Pierce in 2000.
Bianca Andreescu has split with the trainer who helped her win the 2019 U.S. Open championship.
Andreescu posted on societal networking she and Sylvain Bruneau"have mutually decided to finish our unbelievable training relationship."
They worked together for four years.
Bruneau was there once a 19-year-old Andreescu beat Serena Williams from the U.S. Open final to give Canada its first Grand Slam singles decoration.
Andreescu has coped with assorted accidents since and only appeared in two big tournaments.
Tamara Zidansek is your first Slovenian girl to reach a Grand Slam semifinal.
The 85th-ranked Zidansek conquer Paula Badosa of Spain 7-5, 4-6, 8-6 to become the first semifinalist of this year's French Open. She had never been beyond the second round in a Slam prior to this tournament.
Zidansek saved three break points at the penultimate match to endure for a 7-6 lead at the next and then broke Badosa to triumph.
Zidansek will face either Elena Rybakina or Anastasia Pavlyuchenkova for a spot in the closing.
Zidansek was formerly a competitive snowboarder.
Six of the eight women's quarterfinalists in the French Open have never made it so far at Grand Slam tournament.
Former junior champion Paula Badosa of Spain will confront Tamara Zidansek of Slovenia. Zidansek is the first woman from her country to advance so profound at a major.
Rybakina is the third woman from Kazakhstan to reach the quarterfinals at Roland Garros. Pavlyuchenkova already attained this stage in Paris 10 years back.
Second-seeded Daniil Medvedev will perform fifth-seeded Stefanos Tsitsipas from the men's draw. The other men's match will be between No. 6 Alexander Zverev and unseeded Alejandro Davidovich Fokina of Spain. Davidovich Fokina will be playing his first major quarterfinal.