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Designer babies: success through unforeseen mutations?

Unforeseen mutations: More than a year after the birth of the presumed first genetically modified babies in the world, has placed a media report the results of a controversial experiment by the Chinese researcher, He Jiankui out of the question.

In the genome of the two girls there were probably, among other things, unforeseen mutations as a result of genetic engineering, reported in the journal mit Technology Review on Tuesday, citing the Hes research report that the magazine existed. The magazine had interviewed several scientists.

in November 2018 born designer babies with the pseudonym "Lulu" and "Nana" had been begotten according to U through artificial insemination, where the so-called Crispr/Cas9-genetic engineering method for the genetic alteration, also "Genschere" called, was used. He said at that time, he had changed the DNA of the twin pair, so that the two girls were protected against HIV infection.

harsh criticism

The report in the mit Technology Review, invalidated the of He as a "medical breakthrough," a celebrated Experiment. The analysis of the research manuscript, in which the Chinese researchers described his method and results, had confirmed what we had suspected, many experts previously: research report proves the success of his genetic manipulation. Rather, it is supported by the fact that the gene mutation that "resemble", which is immune to HIV, is this but the same.

In addition, showed, according to "mit Technology Review" in the Appendix of the research report contained data that, in other parts of the genome of the twin girls manipulations were made, the consequences of which are yet incalculable.

The controversial Experiment of the Chinese researcher had international triggered sharp criticism and was learning of science as ethically unacceptable convicted. The parents of the twins remained anonymous until today, no Details about the health condition of the two newborns are known. (Dec/sda)

Created: 04.12.2019, 10:02 PM

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