In the United States have caught at the chance. And so the Nih (national institutes of Health) have decided to start immediately a study on the remdesivir in hospitalized patients with Covid-19. The study, randomized controlled trial, is conducted at Omaha, the University of Nebraska Medical Center. Other clinical trials are already underway in China. Not only Ebola Remdesivir, produced by Gilead Sciences, was originally developed to treat Ebola and then gave very encouraging results for the treatment of two other coronaviruses, Mers and Sars. A study of a couple of weeks ago - published in Pnas - has demonstrated how the use of remdesivir in 18 macaques, inoculated 24 hours before exposing the animals to the virus, have managed not only to completely prevent the infection, but inhibit the virus replication in lung tissues, and to prevent the formation of lesions to the lungs. The same medicine - used instead of 12 hours from the inoculation of the virus - has reduced the clinical signs, viral replication in the lungs and the presence and severity of the injury. And then - as the study concludes - so why not use it also for the coronavirus Covid-19, which is creating panic everywhere? A safe and effective treatment In fact this drug has already been used experimentally in some patients with Covid-19. But just because they did not know how to cope with an unexpected situation. What would be the use, stated Anthony Fauci, a scientist of Italian origins among the great experts of Aids and director of the Niaid us National Institute of Allergy and Infectious Diseases) - however a safe and effective treatment. "And even if remdesivir has been used in some patients with Covid-19 - think - there are no solid data to show that it improves clinical outcomes. A randomized, placebo-controlled study, would be the gold standard. The ideal. It starts from the ship to The first participant of the new studio began in the Nebranska is one of the passengers of the americans that has left the 16 of last year, the cruise ship Diamond Princess, was blocked in Japan by the quarantine which has increased dramatically in the cases of infection on board, arrived at over 700. The study involves the administration of remdesivir intravenously in decreasing doses, for ten days. The fifteenth the treated group will be compared with placebo. And the results will be further analyzed after obtaining enough data from one hundred of the participants the initial. The results should not be a long wait, and having a gun secure, certain and effective would change a bit the rules of the game, especially in those countries where the therapies to support breathing are not widespread.
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Carlo Verdelli SUBSCRIBERS TO REPUBLIC © Reproduction reserved Today on the Government, the aim is to store the Count: to the front of the sun set, and it goes Renzi in Giorgetti, The uphill road after the virus there is a great temptation to Take at least one Spoken Angelo Scola: “there is No divine punishment, Milan will make it”