- Coordinated by Michael D. Crowther, John D. Phillips and Andrew K. Sewell, researchers have identified new immune cells, thanks to the technique that cut and paste Dna, the Crispr. In this way they discovered that they belong to the family of the killer cells of the immune system, T lymphocytes, and that on their surface there is a receptor that is very particular, indicated with the acronym Tcr (T-cell receptor). Thanks to it the T cells can recognize molecules present on the surface of many cancer cells, both those that are found on healthy cells. However, the receptor is able to distinguish the first from the second, to kill only the first. No discrimination, instead, for the tumor cells: the receptor is capable of hitting solid tumors and liquid.
T cell receptors so far were able to recognise proteins called human leukocyte Antigen or Hla (human leukocyte antigen), but they couldn't be a weapon univrsale to the fact that the Hla antigen is different from individual to individual. The benefit of new leukocytes T is, instead, to recognize a protein that is double of the Hla, indicated with the acronym Mr1, which does not vary from individual to individual. The latter could then become the new target of immunotherapy, i.e. the strategy, which aims to attack the tumors by hurling against them the immune system.
The first experiments conducted in the laboratory are interesting: the new T cells have been shown to be able to recognize and kill tumors of the lungs, skin, colon, breast, bone, prostate, ovaries, kidneys, and cervix. In all experiments, moreover, have attacked only the cancer cells, ignoring healthy ones. Positive preliminary results obtained in mice altered with human cancer cells and the human immune system.
"The Republic will fight always in defense of the freedom of information, to its readers and to all those who have at heart the principles of democracy and civil coexistence"Carlo Verdelli SUBSCRIBERS TO REPUBLIC © Reproduction reserved Today on The sardines go in Bibbiano, all the while speaking Salvini. On Saturday, the dip in the sea, Papeete the full and The empty of the left Sarditudine, the sound is promising of a word If the logistics was logic Salvini: “The referendum is the"Emilia and I will win”. The former minister pretends to rejoice