Study of hemp-a side effects : ill Who consumed Cannabis daily, often in psychosis

The dispute lasts a long time: a reference to studies that establish a connection between increased Cannabis use and new cases of psychosis. Therefore, Cannabis should not be legalized. Others say that people who are already mentally ill or to be ill, simply grab the more often to drugs such as Cannabis.

The trigger or even the cause of the psychosis or other mental disorders (such as depression) was not the substance and a legalisation could therefore lead to a psychotic-glut. The careful, about 2000 subjects, and eleven places in Europe study carried out under the direction of Marta Di Forti, from the Institute of psychiatry, psychology and neuroscience of the King's College in London, published in the journal "Lancet Psychiatry, speaks well".

The more Cannabis, the more confused the Psyche

While this investigation may result in no clear evidence for Cannabis as cause of psychosis. But it shows that, where Cannabis is freely available, more people with psychosis are diagnosed. Five out of ten of such psychosis cases in London are associated with frequent, daily use of cannabis, in London, there are three out of ten.

in addition, those patients in the study, bringing your body Cannabis a day, three times more likely to have psychosis than Non-users. Among those, the fabric preferred, with particularly high levels of THC (the active ingredient Tetrahydrocannabinol), were among the researchers in the study phase, even five times more psychotic seizures.

"Consistent with previous studies, our results show that the use of Cannabis with high THC concentrations of more a more damaging effect on mental health than the use of less concentrated," says Di Forti. "They also show for the first time how Cannabis turns affects the incidence of mental health new cases in the population." It should be taken into account in the course of the legalization initiatives in various countries is of particular importance for public health, the possible side effects of daily cannabis use.

Would be no Cannabis available, would decrease the psychosis rate to the half

The researchers identified the eleven places in England, the Netherlands, France, Spain and Italy (as well as a place in Brazil) first of all, the number of the psychosis-new krankten between 2010 and 2015, and asked them to participate in the study. 901 agreed to, as well as 1237 in healthy subjects, the eleven regions. They all gave in addition to other health-related information on their consumption behavior with respect to Cannabis and other drugs information, also about the "strength" of the substance.

It turned out that in the group of psychotics significantly more daily Cannabis consumed (244 901, 29 percent) than in the group of Healthy (84 1237, 7 percent). Among the psychosis patients, there were 334 (37 percent), the preferred is particularly strong substance, and among the Healthy there were only 19 percent (240).

Other factors that also trigger psychosis, or transport, were included in the study - such as other drugs such as alcohol, tobacco, or cocaine, but also of education and employment status. The connection between Cannabis and psychosis, was also found in many other studies already did this but no crash.

Unclear stay, however, the extent to which the genetic predisposition of the study participants, or other psychological pre-existing conditions, which has not been asked to contribute to psychosis risk, says Dieter Meyerhoff of the University of California, San Francisco, and also to consume whether the subjects had started using Cannabis before they developed psychosis. "So the possibility of the alternative explanation that participants with first – time psychosis use Cannabis is still-instead of the other way, as the authors explain quite plausible and convincing."

The study was occasion enough, to the legalization of Cannabis, ie the possible consequences. "Unfortunately, we know today, as a society, still much too little about the long-term health consequences of uncontrolled cannabis use, especially among teenagers and young adults." The company had to be very careful. "We use the opportunity to study the relevant developments in the countries that have already legalized Cannabis, before we follow them uncritically."

In Amsterdam, for example, conclude Di Forti and colleagues, from your data, would decrease the incidence rate for psychoses by half, from around 38 cases per 100,000 inhabitants in 19 cases, if Cannabis would be available. In London it would be instead of the 46, only 32 psychosis cases per year.

Also in Germany, the consumer

In Germany is rising Cannabis is not legally available, is consumed in this country yet. Therefore, the results of the study are also transferable to Germany, said Rainer Thomasius, Medical Director of the German centre for addiction issues of the child and youth age at the Hamburg University hospital Eppendorf. the According to the drug and addiction report to 2018 was also increased in Germany, the THC-content in cannabis products in the past few years.

Cannabis-legalization of The smoke-characters

"In the U.S. States that have legalized Cannabis, increased the average THC content as a result of the legalization." There cannabis are in part, products with a 40 - to 50-percent THC content available, says Thomasius. "It is to be feared that the legalization of Cannabis will lead to a significant increase in the risk of Disease with psychosis." (smc)